Xu Kecheng:

Patients are the top priority. This is what Academician Wang Zhenyi and other veteran experts have been looking forward to. On the third day of the Chinese New Year this year, I also visited Academician Tang Zhaoyou in Shanghai. We talked about compound vaccines and the relationship between compound immunity and TLR. He said that in the 1990s, their hospital also used immune preparations similar to Coley toxins. Later, it was found that most of the liver cancer patients who survived for a long time had used this compound immunotherapy.

Xu Kecheng and Academician Tang often discuss new concepts in cancer treatment together

During the Spring Festival in 2024, Xu Kecheng and Academician Tang discussed how to design cancer compound immunity by stimulating TLR.

Member:

What shocked us the most was that your research was from "human" to animal experiments. You have so many clinical cases, which is so valuable. I have read the article you published, which is a prospective survey of 68 cases of advanced cancer receiving compound immunotherapy. I admire it very much!

Xu Kecheng:

From the 1990s to now, for more than 30 years, we have not given up research. This is due to the continuous encouragement of Academician Wang Zhenyi, and thanks to the support of caring entrepreneurs. Many immunology experts in Beijing, Shanghai, Zhengzhou, Guangzhou and other places have given us a lot of advice and guidance. Some experts, such as Professor Lv Youyong of Peking University and Professor Yin Zhinan of Jinan University, also visited our patients. Thank them.

Li Dinggang:

The combination of "Elimination and Transformation" proposed by Academician Tang and "Coexistence with Cancer" proposed by Professor Xu has formed a "cancer control" concept with Chinese characteristics. You can read Tang Zhaoyou's review of "Practicing Chinese-style Cancer Control" compiled by Professor Xu.

"Living with Cancer"

"Practice Chinese Cancer Control"

Member:

As patients, we care not only about the treatment effect, but also about the side effects of the treatment. Does compound immunity have side effects?

Xu Kecheng:

Looking back at the thousands of patients who have been treated with compound immunotherapy from the 1990s to the present, no serious side effects have been found. After the injection, the local area will be red, swollen, and blistered, and the whole body will be hot, generally around 38 degrees Celsius, and last for 1-3 days. Unlike the fever caused by infection, people feel comfortable after the fever. These are all immune responses and expected responses. The injection dose is individualized and adaptive, just to obtain the above-mentioned "moderate" reactions.

Ideal local reaction after injection of compound immune agent

Member:

Can compound immune be used in combination with other treatment methods?

Xu Kecheng:

We hope to use them in combination. It has been proven that the application of immune checkpoint inhibitors requires a good basic immunity as a basis. Compound immunity is to lay the foundation. However, due to the restrictions of "regulations", compound immunity is currently used as a rehabilitation or remedy after "treatment". In addition, as for rehabilitation, the compound immune agent we introduced today can also be used in conjunction with other immune promoters including immune cell infusion (natural killer cells, i.e. NK, DC cells and T cells, etc.). Hydrogen can resist oxidation and inflammation. There is evidence that hydrogen can increase the activity of immune cells and "save" exhausted CD8  T cells. If used together with oxygen, it can improve tumor hypoxia and curb cancer progression. We propose the "cancer rehabilitation promotion trio", which is a combination of compound immune agents, immune cells and hydrogen and oxygen inhalation.

Member:

Professor Xu. Excuse me, are you still injecting this immune combination vaccine?

Xu Kecheng:

Still receiving treatment, but only once every 2-3 months. I "injected" one a few days ago. At the same time, I inhale hydrogen and oxygen every day. It seems that for cancer patients like us, rehabilitation promotion is a lifelong thing.

Summary

Li Dinggang:

From Professor Xu’s introduction just now, I would like to summarize the application of compound immunotherapy, which can be roughly used in the following aspects:

• As a way to prevent recurrence after conventional cancer treatment, especially for patients with a short expected survival period, our respected Professor Xu is like this;

• As a "make up for the loss" after conventional treatment fails, several cases above are like this, including Professor Xu’s sister;

• As part of comprehensive treatment, like the singer with lung cancer brain metastasis in Malaysia;

• As a way to quickly improve symptoms and create conditions for further treatment, like Mr. Shi, who had extensive renal cancer metastasis and failed treatment in the United States;

• Rapidly improve pain, like the English anchor of Shenzhen TV;

• As a means of maintaining immune balance of "coexisting with cancer", like Xiaofeng, who was persuaded by Professor Xu to return for treatment and is now a dance coach in Shenzhen;

• As a means of eliminating residual after treatment and achieving long-term survival, like the outstanding entrepreneur, philanthropist and educator in Indonesia.

Xu Kecheng

Chief physician, professor, doctoral supervisor

Founder of Guangzhou Fuda Cancer Hospital, Jinan University

Honorary Dean of the Institute of Biomedical Translation, Jinan University

Li Dinggang

Chief Physician Professor

Shenzhen Southern University of Science and Technology Cell and Gene Therapy Research Center

Chief Medical Expert

(End of serialization)