About HeRun
About Herun International Center for Preventive Medicine
Fibroblasts Anti-aging

    Causes and mechanisms of aging

      Generally, at the age of 25, the various aging mechanisms of the human body begin to start, various indicators begin to decline, and aging begins from then on.

      Actually, there are many characteristics of aging, not just wrinkles or sagging on the skin. It's just that in the process of aging, skin aging is the most easily noticed part.

      As a person gets older, her skin will become dull, gray and yellow, and will produce spots and wrinkles, and will also sag.

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      The skin is composed of the epidermis, dermis and subcutaneous tissue. The epidermis mainly plays a protective role. The subcutaneous tissue is composed of a large number of fat cells and connective tissue, with a large number of nerves and blood vessels, which mainly provide nutrition. The dermis is mainly composed of a large number of elastic fibers, hyaluronic acid and fibroblasts.

      The number, quality and activity of fibroblasts in the dermis directly determine the degree of skin aging.

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    What are fibroblasts?

      Fibroblasts, also known as fibroblasts, are the main cell components of loose connective tissue and are differentiated from mesenchymal cells in the embryonic period.

      Fibroblasts are large, with clear outlines, and are mostly protruding spindle-shaped or star-shaped flat structures. Their nuclei are regular oval, and the nucleoli are large and obvious. This type of cell accounts for more than 95% of all cells in the dermis. It can be said that the maintenance of the structure and function of the entire dermis is maintained by fibroblasts, the main force, thus maintaining the firmness, elasticity and moisture of the skin.

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      With the increase of age, the number of fibroblasts in the skin decreases, the function declines, and the synthesis of collagen and elastic fibers decreases. The secretion of hyaluronic acid decreases, the skin gradually becomes dry, loses elasticity, begins to sag, and dry lines and wrinkles appear.

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    Principle and function of autologous fibroblasts

    Biological principle of autologous fibroblast regenerative therapy

      When the skin becomes dry, loose and wrinkled, increasing fibroblasts becomes a "fundamental" treatment, which is equivalent to tracing the source directly. It is more thorough than a series of measures such as indirect supplementation of collagen.

    Mechanism of fibroblasts

      Autologous fibroblasts can synthesize collagen, elastic fibers, and hyaluronic acid to fill the gaps of skin aging, fill the traces of aging, regenerate and repair skin damage, and achieve skin reverse growth; comprehensively improve wrinkles on the face, neck, and hands, and make the skin younger.

    Fibroblast anti-aging

      Fibroblasts are an important cell type in the human body. Their main function is to participate in tissue repair and regeneration, and they have special anti-aging abilities. Their main function is to produce structural proteins such as collagen and elastin to maintain the structure and function of tissues. In addition, fibroblasts can promote angiogenesis, eliminate blood toxins, and inhibit malignant changes in cells, thereby ensuring human health.

      Fibroblasts have a long lifespan, so their anti-aging ability is also more prominent. However, during the long-term cell metabolism process, fibroblasts will be damaged by various factors, such as free radicals, ultraviolet rays, etc. These damages will lead to cell apoptosis and functional decline.

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    Autologous fibroblast regeneration therapy physical examination items

    Must-check physical examination before skin removal

    • Blood routine

    • Eight items of infection

    • Four items of coagulation

    • ECG

    Must-check physical examination before reinjection

    • Blood routine

    • Eight items of infection

    • Four items of coagulation

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    How to improve the anti-aging ability of fibroblasts

    • Proper amount of exercise

      Proper amount of exercise also has a positive effect on the anti-aging of fibroblasts. Exercise can increase blood circulation, increase the supply of oxygen and nutrients, and promote the excretion of waste in the body, which is beneficial to maintain the stability of the internal environment of the cell eukaryotic membrane and maintain the normal function of cells. In addition, exercise can also improve the ability to scavenge free radicals, reduce cell oxidative stress, and enhance the anti-aging ability of fibroblasts.

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    • Sufficient sleep

        Studies have shown that adequate sleep can have a positive effect on the anti-aging of fibroblasts. During sleep, the biological clock inside the human body will adjust the metabolic process to the optimal state and maintain the balance of cell metabolism. In addition, sleep can also promote the secretion of HGH (growth hormone), which is one of the important hormones of fibroblast metabolism, and can enhance the self-repair function and anti-aging ability of fibroblasts.

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    • Reasonable diet

        Scientists have found that a diet containing enough antioxidants (vegetables, fruits, etc.) and proteins (chicken, fish, eggs, etc.) has a good promoting effect on cell anti-aging. In addition, a moderate amount of saturated fatty acids (dairy products, meat, etc.) and inorganic salts (calcium, iron, zinc, etc.) are also beneficial to cell health. At the same time, appropriately reducing the intake of artificial trans fats, high-sugar, and high-salt diets can help prevent cell aging and disease.

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    Advantages of fibroblasts and related cases

      Autologous skin fibroblasts for facial anti-aging stimulate dormant and aging cells. With the nourishment of fresh cells, the body becomes young and active, and surface problems can naturally be improved, and the skin is as white and rosy as before, shining.

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    Advantages of fibroblasts

    • Safety

      Autologous cell therapy will not produce side effects such as immune rejection;

    • Persistent

      Autologous cells have a long-term effect and the effect is long-lasting;

    • Healthy

      It does not damage or stimulate pathological changes in the skin, nor is it a foreign body filler. It achieves its purpose by naturally enhancing skin function;

    • Natural

      It is a physiological beauty treatment that does not affect the facial expression muscles and ligaments of the patient, and the expression is natural and harmonious.

    • Widely

      Autologous fibroblast regeneration therapy uses autologous cells to eliminate the problem of rejection, so it can be widely used in cosmetic surgery.

    Eight core highlights of skin fibroblast facial implantation

    • Highlight 1: Deep wrinkle removal, ideal for deep wrinkles or scars;

    • Highlight 2: Thicken and plump skin, autologous fibroblasts activated regeneration and repair;

    • Highlight 3: Long-term continuous repair, continuous rejuvenation within 3-5 years after conditioning;

    • Highlight 4: Intelligent facial micro-surgery, optimizing muscle age according to facial tissue morphology;

    • Highlight 5: Intelligent facelift and rejuvenation, generating elastic fibers to enhance facial contours;

    • Highlight 6: Safe and without side effects, non-foreign cell products have no side effects;

    • Highlight 7: Real traceless beauty, no instrument can detect any traces of conditioning;

    • Highlight 8: Widely used internationally, it is the facial rejuvenation solution for international celebrities.

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    Applicable people


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